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Patients with MIS-C usually present with persistent fever, abdominal pain, vomiting, diarrhea, skin rash, mucocutaneous lesions and, in severe cases, with hypotension and shock.

Consider MIS-C in any pediatric death with evidence of SARS-CoV-2 infection.

Some individuals may fulfill full or partial criteria for Kawasaki disease but should be reported if they meet the case definition for MIS-C.

**Including, but not limited to, one or more of the following: an elevated C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), fibrinogen, procalcitonin, d-dimer, ferritin, lactic acid dehydrogenase (LDH), or interleukin 6 (IL-6), elevated neutrophils, reduced lymphocytes and low albumin *Fever >38.0вЊ for в‰Ґ24 hours, or report of subjective fever lasting в‰Ґ24 hours

Positive for current or recent SARS-CoV-2 infection by RT-PCR, serology, or antigen test or exposure to a suspected or confirmed COVID-19 case within the 4 weeks prior to the onset of symptoms.

No alternative plausible diagnoses AND.

An individual aged 2) organ involvement (cardiac, renal, respiratory, hematologic, gastrointestinal, dermatologic or neurological) AND.

WHERE SHOULD I DOWNLOAD SERUM PDF

Download and print the Reporting MIS-C fact sheet pdf icon to learn more.ДЄs described in the CDC Health Advisory, вЂњ Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19),вЂќ the case definition for MIS-C is: Questions? Contact CDCвЂ™s 24-hour Emergency Operations Center at 77. Report possible cases of MIS-C to your local, state, or territorial health department.

Reporting Multisystem Inflammatory Syndrome in Children (MIS-C)

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